Can Class II Biological Safety Cabinet designs be improved to reduce laboratory-associated infections?
By Gregor Riese (Published on January 27, 2025)
This project was a runner-up for the "Novel research (qualitative)" prize on our Pandemics (Sept 2024) course. The text below is an excerpt from the final project.
Abstract
Class II Biological Safety Cabinets (BSCs) are the primary containment device protecting workers in BSL2, BSL3 and BSL4 laboratories. BSCs rely on High-Efficiency Particulate Air (HEPA) filters and negative pressure to entrap aerosolised pathogens and limiting the risk of laboratory workers being exposed. This paper examines the performance of Class II BSCs in seeking to limit laboratory associated infections (LAIs). We also examine modifications to Class II BSCs which could reduce the risks of LAIs.
Full project
You can view the full project here.